Johnny Test
Young Johnny is gung-ho and full of courage. Johnny's brainiac twin sisters, Susan and Mary, use Johnny as their guinea pig for their outrageous scientific experiments. If they can dream it up, Johnny will do it; as long as his genetically engineered super dog, Dukey, can come along.

Season 3 · Episode 13 ·
Johnnyitis
Johnny drinks an unstable isotope so he can get sick and not have to study for a test for school. Unfortunately, not only does the isotope give him red spots and a purple tongue, if it's not cured within four hours, it's going to give him immense bloating, cause violent coughing, and eventually make him explode.
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Episode 13 of season 3 of Johnny Test: “Johnnyitis”. Aired 2007-10-27. Watch it online free on ZapFlix.