Totally Spies!
Totally Spies! depicts three girlfriends 'with an attitude' who have to cope with their daily lives at high school as well as the unpredictable pressures of international espionage. They confront the most intimidating - and demented - of villains, each with their own special agenda for demonic, global rude behavior.

Season 2 · Episode 21 ·
Brain Drain
Sam wins a spot on the hot new game show, 'The Main Brain.' The following day, when Sam begins to lose her memory. Investigation by Alex and Clover reveals that game show host Larry Large is stealing his contestants brainpower and putting it into the mind of his waitress-girlfriend, Margie so that they can dominate the airwaves and eventually the world!
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Episode 21 of season 2 of Totally Spies!: “Brain Drain”. Aired 2003-06-18. Watch it online free on ZapFlix.