Dexter's Laboratory
Dexter, a boy-genius with a secret laboratory, constantly battles his sister Dee Dee, who always gains access despite his best efforts to keep her out, as well as his arch-rival and neighbor, Mandark.

Season 2 · Episode 56 ·
G.I.R.L. Squad
Dee Dee, LeeLee and MeeMee become crimefighters, but of course they will not actually fight crime.
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Episode 56 of season 2 of Dexter's Laboratory: “G.I.R.L. Squad”. Aired 1997-11-26. Watch it online free on ZapFlix.